There's no substitute for playing the Open Sicilian if you're White. There are a number of plausible anti-Sicilians, but none offer the opportunity to score the full point offered by taking on the mass of theory. When playing the open Sicilian, it's possible to land in a classical Sicilian by many routes, including 2...d6, 2...e6, or 2...Nc6. If you do, consider the Richter Rauzer.
The ICC bots are a good way to test your openings when it's difficult to find an opponent.